Botulinum neurotoxins (BoNTs) are the most poisonous substances known to humans, with a median lethal dose (LD50) of 1ng per kg of body weight and are the cause of the life-threatening neuroparalytic illness botulism. Recent assays are very promising for practical use, they require expensive and technically complex equipment. Meeting a need for further development of assays for detection of BoNTs, researchers now have developed a nanopore-based assay for detection of BoNT-B.
Nanotechnology applications are currently being researched, tested and in some cases already applied across the entire spectrum of food technology, from agriculture to food processing, packaging and food supplements. Specifically in agriculture, technical innovation is of importance with regard to addressing global challenges such as population growth, climate change and the limited availability of important plant nutrients. Nanotechnology applied to agricultural production could play a fundamental role for this purpose and research on agricultural applications is ongoing for largely a decade by now.
Nanotechnology, specifically nanomaterial engineering, has begun to find applications in agriculture and the food industry. Some nanomaterials have unique physicochemical properties that can be exploited for beneficial effects on foods, leading to increased shelf life, enhanced flavor release, and increased absorption of nutrients and other bioactive components. The ability to detect and to measure a given nanomaterial at key time points in the food lifecycle is critical for estimating the nanoscale properties of interest that dictate manufacturing consistency and safety, as well as understanding potential beneficial or adverse effects from food intercalation.
Some of the recent and significant developments in the area of nanotechnology applications for food quality control are discussed in this article. In food quality testing methods/devices, nanomaterials have various advantages over conventional materials such as ultra-sensitivity, selectivity, multiple targeting, portability, reproducible data processing, implantable conformability, on-board intelligence, non-invasive testing of packaged items, etc. Analytical chemistry plays a prominent role in food quality control and has already started taking advantages from the versatility and novel merits of nanoscience.
Nanotechnology-based food and health products and food packaging materials are available to consumers in some countries already, and additional products and applications are currently in the research and development stage, and some may reach the market soon. In view of such progress, it is expected that nanotechnology-derived food products will be increasingly available to consumers worldwide in the coming years. Some of these products appear to already be in commercial use in other countries, raising the likelihood that they could become a part of our food supply in the near future, if they are not already. This article looks at how regulators are dealing with the pressures to commercialize nanotech foods and food packaging.
Following up on our recent Nanowerk Spotlight on nanofoods, new research shows that consumers could be exposed to nanoparticles in food by a much larger degree than has been expected so far. For a modern consumer it is hard to avoid titanium dioxide (TiO2) - a widely used additive in food, personal care and other household products. Approximately 7 million tons of bulk TiO2 are produced annually and used as white pigment in order to provide whiteness and opacity to foods and other products. Many applications of titanium dioxide would benefit from smaller primary particle sizes, and we can expect the percentage of TiO2 that is produced in or near the nano range to increase.
Back in the early 2010s, food nanotechnology seemed to be a very hot topic and large industrial food companies were eager to explore new opportunities offered by nanotechnology applications. Then, as critical voices from NGOs and regulators appeared, the food industry went into silent mode. But that doesn't mean that food nanotechnologies aren't being researched and developed in labs around the world. Here is an overview of what nanotechnology applications are currently being researched, tested and in some cases already applied in food technology. It appears that we are still some way from seeing "Frankenfoods" in supermarket shelves. According to a recent commentary by an FDA official, what's holding back the introduction of nanofoods is the hesitation of the food industry, fearing a public backlash along the lines of what happened wit genetically modified foods.
Over the past few years, scientists have taken advantage of the unique optical and other physical properties of metal nanoparticles to create a wide range of nanotechnology probes for electronic, optical, and microgravimetric transduction of different biomolecular recognition events. An interesting approach that was reported a couple of years ago deals with a technique that estimates the antioxidant power of certain food samples by measuring the generation and growth of gold nanoparticles. Researchers have built on these findings by developing a novel optical nanoprobe that can analyze the total reducing sugar content of samples. This technique could lead to the development of inexpensive and disposable optical nanoprobes that could find applications in a host of industrial, biomedical and clinical fields.