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CRISPR-Cas9 can generate unexpected, heritable mutations

In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation. These scientists therefore urge caution and meticulous validation before using CRISPR-Cas9 for medical purposes.

Feb 2nd, 2022

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Scientists regrow frog's lost leg

Regrowth of legs and arms remains the province of salamanders and superheroes. But in a new study, scientists have brought us a step closer to the goal of regenerative medicine.

Feb 2nd, 2022

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Improved retinal transplant technique ready for clinical trials

Researchers have used a genetic modification to improve human-derived retina transplants grown in the lab. After transplant into damaged mouse retinas, timed removal of certain cells from the grafts allowed better connections to host retinas, which resulted in more responsiveness to light in the damaged eyes.

Jan 27th, 2022

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Illuminating a biological light switch

Using an innovative new imaging technique, researchers have revealed the inner workings of a family of light-sensing molecules in unprecedented detail and speed. The work could inform new strategies in the burgeoning field of optogenetics, which uses light pulses to alter the activity of individual neurons and other cells.

Jan 26th, 2022

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Fat-burning hydrogel fights obesity (w/video)

Scientists have developed a new therapeutic approach to obesity and related metabolic disorders that in laboratory experiments demonstrated a significant reduction in body fat, body weight, and improvement in the blood markers that accompany these disorders.

Jan 26th, 2022

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