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Tissue development 'roadmap' created to guide stem cell medicine

In a boon to stem cell research and regenerative medicine, scientists have created a computer algorithm called CellNet as a 'roadmap' for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

Posted: Aug 14th, 2014

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Researchers identify key mechanism that drives movement in living cells

Scientists discovered that living cell migration is regulated by the engagement of a force transmitter composed of vinculin and talin, two types of cytoskeletal protein. The researchers showed that force-dependent vinculin binding to talin plays a critical role in mechanically connecting the actin cytoskeleton to the extracellular substrate to contribute towards cell migration.

Posted: Aug 14th, 2014

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Bacterial biosurgery shows promise for reducing the size of inoperable tumors

Deep within most tumors lie areas that remain untouched by chemotherapy and radiation. These troublesome spots lack the blood and oxygen needed for traditional therapies to work, but provide the perfect target for a new cancer treatment using bacteria that thrive in oxygen-poor conditions. Now, researchers have shown that injections of a weakened version of one such anaerobic bacteria can shrink tumors in rats, pet dogs, and a human patient.

Posted: Aug 13th, 2014

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Coming soon: Genetically edited fruit?

Recent advances that allow the precise editing of genomes now raise the possibility that fruit and other crops might be genetically improved without the need to introduce foreign genes.

Posted: Aug 13th, 2014

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How spiders fix their webs

Spider silk is light and delicate, while incredibly resilient and tear-resistant. Understanding the structure and way of construction of these threads is a challenge taken up by a research team of Kiel University.

Posted: Aug 13th, 2014

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To watch DNA unwrap, blank out the proteins

Biophysics is a science of shapes - the shapes of molecules like DNA as they wrap and unwrap around protein cores, for instance. Researchers have unveiled a new method for observing such processes in real time.

Posted: Aug 12th, 2014

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Synthetic molecule makes cancer self-destruct

Researchers have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells. These synthetic ion transporters confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefitting patients with cystic fibrosis.

Posted: Aug 11th, 2014

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Cryoprinting red blood cells

An innovative approach of cryopreserving red blood cells using vitrification in conjunction with bio-printing technologies has been described in a new collaborative study.

Posted: Aug 11th, 2014

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The interior of a cell from a moving protein's point of view

Numerous obstacles posed by cellular structures hinder protein movements within the cell. Researchers now have succeeded in mapping the intracellular topology by observing proteins in living cells on multiple time and length scales. By developing a new fluorescence microscopy-based technique, the researchers were able to measure how long it takes proteins to move over distances ranging from 0.2 to 3 micrometres in living cells.

Posted: Aug 11th, 2014

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