Scientists at the SUNY College of Environmental Science and Forestry (ESF) are developing a biochemical process that uses a protein molecule to disrupt the process by which bacteria become virulent, a finding that could have widespread implications for human health.
While working out the structure of a cell-killing protein produced by some strains of the bacterium Enterococcus faecalis, researchers stumbled on a bit of unusual biochemistry. They found that a single enzyme helps form distinctly different, three-dimensional ring structures in the protein, one of which had never been observed before.
A new metabolic engineering tool that allows fine control of gene expression level by employing synthetic small regulatory RNAs was developed to efficiently construct microbial cell factories producing desired chemicals and materials.
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins.
Genes make up only a minority of the entire genome sequence - roughly two percent in humans. The remainder was once dismissed as "junk", mostly because its function remained elusive. "Dark matter" might be more appropriate, but gradually light is being shed on this part of the genome, too.
Fraunhofer researchers are exhibiting how renewable, biodegradable and biostable raw materials can be used in architecture, interior design and the packaging industry at this year's International Green Week in Berlin.
Researchers from the University of Bonn treated mice with Viagra and made an amazing discovery: The drug converts undesirable white fat cells and could thus potentially melt the unwelcome 'spare tire' around the midriff.
Researchers from ETH Zurich have filed a patent application for a method to test the biological activity of one of the strongest toxins known, the botulinum neurotoxin. If the procedure is adopted by the pharmaceutical industry, it could save the lives of more than half a million mice per year.
A non-invasive method that makes it possible to observe in situ how assemblies of lipids are oriented in biological tissues, and which does not require any labeling or preparation, has been developed by physicists.
Researchers at The University of Texas at Austin have developed a menu of 61 new strains of genetically engineered bacteria that may improve the efficacy of vaccines for diseases such as flu, pertussis, cholera and HPV.