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Gene regulation at its brightest

Scientists have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

Mar 18th, 2022

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Inhalable aerogel triggers immunity to COVID-19 in mice, may block transmission

An inhalable aerogel loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice. The scientists said its aerogel could be used to create an inhalable vaccine that blocks SARS-CoV-2 transmission by preventing the virus from establishing an infection in the lungs.

Mar 16th, 2022

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Using mRNA delivery to improve muscle strength

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. Scientists have now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

Mar 14th, 2022

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A speed limit could be a breakthrough for stem cell therapy

Replacing sick or damaged cells with healthy cells: this is a major goal of regenerative medicine. One of the most promising approaches is cellular reprogramming, whereby one cell type in our body converts to another cell type. Researchers have discovered new ways to improve the cellular reprogramming efficiency, unlocking potential for cellular repair therapies.

Mar 7th, 2022

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Cannabinoids from amoebae

Researchers have developed a new method to produce complex natural products in amoebae. These polyketides include various antibiotics but also olivetolic acid, a precursor of the herbal active ingredient tetrahydrocannabinol (THC).

Mar 4th, 2022

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