With the Uniqprobe series NANOSENSORS™ offers AFM probes that are especially dedicated for applications in biology, biophysics and life-sciences.

Their most important feature is their uniformity of AFM cantilever thickness.

Because of this NANOSENSORS can offer very soft AFM cantilevers with a very low variation in force constant and resonance frequency.
This is especially important when reproducible data for quantitative measurements of nanomechanical properties are required.

The special reflex coating applied to Uniqprobes for biological applications results in AFM cantilevers with low thermal drift and make them very attractive for applications in liquid.

The AFM tip of the standard Uniqprobes has a circular symmetric shape with a hyperbolic profile. The AFM tip height is around 7 µm and the typical tip radius is smaller than 10 nm.
( Exception: qp-BioAC-CI with a deliberately rounded AFM tip for cell imaging which as a typical tip radius of around 30 nm.)

The following Uniqprobes for biological applications are currently available:

qp-CONT – rectangular cantilever:
Typical force constant: 0.1 N/m
Typical resonance frequency: 30 kHz

qp-SCONT – rectangular cantilever:
Typical force constant: 0.01 N/m
Typical resonance frequency: 11 kHz

qp-BioT – two different triangular AFM cantilevers

Typical force constant:
Cantilever beam 1 (CB1): 0.3 N/m
Cantilever beam 2 (CB2): 0.08 N/m

Typical resonance frequency:
Cantilever beam 1 (CB1): 50 kHz
Cantilever beam 2 (CB2): 20 kHz

qp-BioAC – three different rectangular AFM cantilevers:

Typical force constant:
Cantilever beam 1 (CB1): 0.3 N/m
Cantilever beam 2 (CB2): 0.1 N/m
Cantilever beam 3 (CB3): 0.06 N/m

Typical resonance frequency:
Cantilever beam 1 (CB1): 90 kHz
Cantilever beam 2 (CB2): 50 kHz
Cantilever beam 3 (CB3): 30 kHz


qp-BioAC-CI – a version of uniqprobe™ BioAC with Rounded AFM Tips for Cell Imaging

Typical force constant:
Cantilever beam 1 (CB1): 0.3 N/m
Cantilever beam 2 (CB2): 0.1 N/m
Cantilever beam 3 (CB3): 0.06 N/m

Typical resonance frequency:
Cantilever beam 1 (CB1): 90 kHz
Cantilever beam 2 (CB2): 50 kHz
Cantilever beam 3 (CB3): 30 kHz

Additionally tipless versions of the qp-SCONT, qp-CONT and the qp-BioT ( SD-qp-BioT-TL, SD-qp-CONT-TL, SD-qp-SCONT-TL) and uniqprobe tipless AFM cantilever arrays ( SD-qp-TL8a and SD-qp-TL8b ) are available from the NANOSENSORS special developments list: https://www.nanosensors.com/pdf/SpecialDevelopmentsList.pdf

A special qp-fast for high-speed imaging is also available.

Please contact us for further information of have a look at: http://www.nanosensors.com/pdf/NANOSENSORS-uniqprobe-brochure.pdf

Application examples can be found in the NANOSENSORS blog https://www.nanosensors.com/blog/?s=uniqprobe