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CRISPR/Cas9 technology to inactivate cancer mutations

As for many other biomedical and biotechnology disciplines, the genome scissor CRISPR/Cas9 also opens up completely new possibilities for cancer research. Scientists have shown that mutations that act as cancer drivers can be targeted and repaired. The most relevant mutations could therefore be diagnosed faster, improving personalized therapies.

Aug 31st, 2016

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Algorithms offer insight into cellular development

Through RNA sequencing, researchers can measure which genes are expressed in each individual cell of a sample. A new statistical method allows researchers to infer different developmental processes from a cell mixture consisting of asynchronous stages.

Aug 31st, 2016

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Bringing artificial enzymes closer to nature

Scientists have developed an artificial metalloenzyme that catalyses a reaction inside of cells without equivalent in nature. This could be a prime example for creating new non-natural metabolic pathways inside living cells.

Aug 29th, 2016

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A look at the molecular quality assurance within cells

Proteins fulfill vital functions in our body. They transport substances, combat pathogens, and function as catalysts. In order for these processes to function reliably, proteins must adopt a defined three-dimensional structure. Molecular 'folding assistants', called chaperones, aid and scrutinize these structuring processes. Researchers have now revealed how chaperones identify particularly harmful errors in this structuring process.

Aug 25th, 2016

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Hacking microbes

Startup's engineered yeast helps clients produce fragrances and flavors more efficiently.

Aug 25th, 2016

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Catching proteins in the act

Scientists have successfully shown how the ultrafast processes by which proteins do their work can be studied with free-electron X-ray lasers. As a model organism, they used a simple microbe that can convert light into chemical energy.

Aug 22nd, 2016

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Biophysics: Stopping the random walk

The cell's internal skeleton undergoes constant restructuring. Physicists show that its associated proteins can be efficiently transported to their sites of action by diffusion - provided they can be arrested when they get there.

Aug 17th, 2016

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