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Using mRNA delivery to improve muscle strength

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. Scientists have now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

Mar 14th, 2022

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A speed limit could be a breakthrough for stem cell therapy

Replacing sick or damaged cells with healthy cells: this is a major goal of regenerative medicine. One of the most promising approaches is cellular reprogramming, whereby one cell type in our body converts to another cell type. Researchers have discovered new ways to improve the cellular reprogramming efficiency, unlocking potential for cellular repair therapies.

Mar 7th, 2022

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Cannabinoids from amoebae

Researchers have developed a new method to produce complex natural products in amoebae. These polyketides include various antibiotics but also olivetolic acid, a precursor of the herbal active ingredient tetrahydrocannabinol (THC).

Mar 4th, 2022

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Gene editing gets safer thanks to redesigned Cas9 protein

Scientists have redesigned a key component of a widely used CRISPR-based gene-editing tool, called Cas9, to be thousands of times less likely to target the wrong stretch of DNA while remaining just as efficient as the original version, making it potentially much safer.

Mar 2nd, 2022

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