The Proteostasis initiative, supported by the European Union (EU), is led by the Basque centre for research in biosciences, CIC bioGUNE, in collaboration with the Inbiomed foundation, and includes groups that carry out research on the degradation and modification of cellular proteins.
Jan 13th, 2014
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Scientists at EMBL-EBI have developed EC-BLAST: software that makes it easier to develop novel enzymes.
Jan 13th, 2014
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Findings allow for better understanding of how tissue microenvironment affects gene expression in healthy and diseased cells.
Jan 12th, 2014
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Harvard stem cells scientists at Brigham and Women's Hospital and MIT can now engineer cells that are more easily controlled following transplantation, potentially making cell therapies, hundreds of which are currently in clinical trials across the United States, more functional and efficient.
Jan 10th, 2014
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When autologous, skin-derived stem cells were transplanted within collagen nerve guide tubes aimed at bridging gaps in damaged nerves, into the upper arms of a patient who was suffering peripheral nerve damage, the procedure successfully led to the rescue of peripheral nerves. The procedure spared the patient with poly-injury to motor and sensory nerve damage from amputation of the upper arms and resulted in 'suitable functional recovery'. Three year follow up revealed nerve regeneration.
Jan 10th, 2014
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Artificial bone marrow may be used to reproduce hematopoietic stem cells. A prototype has now been developed. The porous structure possesses essential properties of natural bone marrow and can be used for the reproduction of stem cells at the laboratory.
Jan 10th, 2014
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A team of researchers led by scientists from the American Museum of Natural History has released the first report of widespread biofluorescence in the tree of life of fishes, identifying more than 180 species that glow in a wide range of colors and patterns.
Jan 9th, 2014
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A new method for analysing biological samples based on their chemical makeup is set to transform the way medical scientists examine diseased tissue.
Jan 8th, 2014
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Rice University leads study to counter effects of temperature on synthetic gene circuits.
Jan 7th, 2014
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Scientists at The New York Stem Cell Foundation Research Institute, working in collaboration with scientists from Columbia University Medical Center, for the first time generated induced pluripotent stem cells lines from non-cryoprotected brain tissue of patients with Alzheimer's disease.
Jan 7th, 2014
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With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become bone-building cells.
Jan 6th, 2014
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For about 20 years now, experimental research on nuclear DNA has been supplemented by research based on computer simulations aimed at reconstructing the structure and function of this molecule that is so essential to life as we know it. A systematic review - carried out with the participation of SISSA in Trieste - provides a detailed summary of the majority of models developed to date. The review is mainly aimed at biologists, for whom it may become an important research tool.
Jan 3rd, 2014
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Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes. The finding is important for the field of epigenetics because Tet enzymes chemically modify DNA, changing signposts that tell the cell's machinery 'this gene is shut off' into other signs that say 'ready for a change'.
Dec 26th, 2013
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Chemists have caught molecules in the act of biosynthesis revealing an animated view of how a fundamental piece of cellular machinery operates.
Dec 23rd, 2013
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Scientists at the University of York have made a significant step in the search to develop effective second generation biofuels.
Dec 22nd, 2013
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Researchers map cell's complex genetic interactions to fix damaged DNA.
Dec 20th, 2013
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New molecular tools for controlling production of compounds important for flavors, human health, and biofuels.
Dec 20th, 2013
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The natural ability of certain fungi to break down complex substances makes them very valuable microorganisms to use as cell factories in industrial processes. Advances in metabolic engineering and systems biology are helping to customize and optimize these fungi to produce specific bioproducts.
Dec 19th, 2013
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