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Nanowerk Spotlight

Behind the buzz and beyond the hype: Our daily Nanowerk-exclusive nanotechnology feature article. Some stories are more like an introduction to nanotechnology, some are about understanding current developments, and some are advanced reviews of leading edge research.
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Showing spotlights 1 - 6 of 790 in category All (newest first):

Fluorescent gold nanoprobes for real-time detection of reactive oxygen species
fluorescent_ROS_imagingPosted: Jul 2nd, 2009
Environmental and behavioral factors may lead the body to produce superoxide radicals known as reactive oxygen species (ROS) that could cause cell damage through oxidation. Oxidative stress from ROS is implicated in aging and most diseases including cancer, heart disease, liver fibrosis, neurodegenerative diseases, autoimmune disorders. An excess of these reactive molecules can lead to oxidative stress and cellular damage, and toxicologists have identified ROS generation as a likely mechanism of nanoparticle toxicity. Since ROS plays an important role in various pathogenic processes, it has been recognized as an early indicator for cytotoxic events and cellular disorders. However, conventional chemical ROS probes have not fulfilled the rising need of in vitro and in vivo analysis of ROS generation due to auto-oxidation problems and poor specificity and sensitivity. Scientists in South Korea have now demonstrated a novel ROS-sensitive gold nanoprobe prepared from bio-inspired immobilization of fluorescein-labeled hyaluronic acid onto the surface of gold nanoparticles. This probe is highly stable under exposure to natural light and laser sources and extremely sensitive and specific to certain oxygen species.... nanotechnology article
Nanoarches advance nanotechnology's tool box
nanoarchPosted: Jul 1st, 2009
One of the ultimate goals of nanotechnology is to fabricate functional devices at the nanoscale. A nanodevice is expected to integrate components of different material compositions and geometries. The integration is likely to be carried out on silicon if information processing is required. Thus far, the basic building blocks for nanodevices are nanoparticles, for which there are many material candidates; and nanotubes, for which the candidates are fewer (they are mostly carbon, although non-carbon based tubes have been fabricated as well). One-dimensional (1-D) nanomaterials such as nanotubes are useful for component connection and for the transport of charge, heat and vibration. In addition to the limited material selection, common 1-D nanomaterials are usually straight. Composite 1-D nanomaterials are rarer. Often they are also produced as discrete and unorganized units. Scientists in Singapore have now successfully fabricated a family of aligned one-dimensional C-curved nanoarches of different compositions by a simple and scalable method for the first time. ... nanotechnology article
Nanotechnology PacMan cuts straight graphene edges
PacManPosted: Jun 30th, 2009
Graphene has two distinct types of edges produced when it is cut - armchair type or zigzag type - which correspond to the two crystal axis of graphene. These edge types are predicted theoretically to have distinct electronic, magnetic, and chemical properties, but current fabrication methods have no way of controlling which type of edge is produced and are dominated by disorder. For example, a common method is to use plasma etching which is an isotropic etching process and is not selective in which crystallographic direction it etches. This is a problem in especially nanoelectronics applications and devices where the potential performance of the device depends strongly on the edge structure as well. A solution to this problem has now been found. Researchers have demonstrated anisotropic etching in single-layer graphene which produces connected graphene nanostructures with crystallographically oriented edges. This opens many future avenues to study graphene nanostructures such as nanoribbons, nanoconstrictions, and quantum dots with crystallographic edges.... nanotechnology article
How to make nanosilver non-cytotoxic with sugar
silver_nanoparticlesPosted: Jun 29th, 2009
You can find them in all kinds of products, from socks to food containers to coatings for medical devices - we are talking about silver nanoparticles. Valued for its infection-fighting, antimicrobial properties, silver in its modern incarnation as silver nanoparticles, has become the promising antimicrobial material in a variety of applications because the nanoparticles can damage bacterial cells by destroying the enzymes that transport cell nutrient and weakening the cell membrane or cell wall and cytoplasm. Despite their wide use, the issue of possible adverse effects and toxicity of nanoparticles for the human body is progressively, albeit slowly, recognized as central by an increasing number of studies. A widely accepted consensus on the detailed molecular mechanism of silver nanoparticles toxicity is still missing and very often the drive toward new formulations overwhelms the interest for a better assessment of the cytotoxicity of the nanoparticles. Scientists at the University of Trieste in Italy have now developed a novel non-cytotoxic nanocomposite hydrogel material based on natural polysaccharides and silver nanoparticles for antimicrobial applications.... nanotechnology article
Observing carbon nanotubes can damage them - even at 80 kV
carbon_nanotubePosted: Jun 25th, 2009
A few days ago we ran a Nanowerk Spotlight on a nanostructuring technique that uses an extremely narrow electron beam to knock individual carbon atoms from carbon nanotubes with atomic precision, a technique that could potentially be used to change the properties of the nanotubes. In contrast to this deliberately created defect, researchers are concerned about unintentional defects created by electron beams during examination of carbon nanomaterials with transmission electron microscopes like a high-resolution transmission electron microscope (HRTEM). For a long time it has been thought that if the accelerating voltage of electrons could be reduced to 80 kV in an electron microscope, then the electrons would not possess sufficient energy to cause knock-on damage in carbon nanomaterials. Knock-on damage occurs when electrons are scattered by the nucleus of the atom they are probing. Upon scattering, energy is transferred. In some circumstances this energy can be large enough to dislodge the atom from its position. A British-German team has examined how electrons accelerated at 80 kV interact with singe-walled carbon nanotubes and shown that in some circumstances SWCNTs were unstable. ... nanotechnology article
Humidity doesn't interfere with this nanotechnology gas sensor
humidityPosted: Jun 23rd, 2009
Gas sensing applications are numerous in our modern society and include process monitoring, environmental compliance, health applications, homeland security, agriculture, etc. Gas sensors often operate by detecting the subtle changes that deposited gas molecules make in the way electricity moves through a surface layer. Thus, the more surface available, the more sensitive the sensor will be. Nanoscale materials are intriguing materials for next-generation nanotechnology gas sensors since their relative surface areas are so large. A problem with existing gas nanosensors is the cross-interference of other gas analytes. For instance, carbon nanotube based gas sensors for the prominent air pollutant nitrogen dioxide have shown strong interference of ethanol and ammonia gases to the NO2 response. Another cross-interference often is caused by humidity, i.e. the water vapor in the air. New research now demonstrates how the manufacturing of a nanosensor for ammonia gas can be tuned to eliminate the interference of water vapor. The trick lies in accurately controlling the synthesis of the sensing nanomaterial.... nanotechnology article


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