Since its discovery, researchers have hailed Cas9 - a protein 'machine' that can be programmed by a strand of RNA to target specific DNA sequences and to precisely cut, paste, and turn on or turn off genes - as a potential key to unlocking a host of new treatments and therapies for genetic conditions, but only if they fully understand how it works.
Chemists from Nijmegen have developed a catalyst that binds to DNA, slides over it and splits the molecule in particular places. The researchers were able to do this by synthetically modifying a natural catalyst.
Reprogramming adult stem cells so that they are like embryonic stem cells has the potential to change medicine; however, the reprogramming process is inefficient and impractical. Now, Dr. Yaqub Hanna has found that removing one protein changes everything, raising the efficiency of this reprogramming from one percent or less to 100 percent.
Researchers at the Arizona Center for Algae Technology and Innovation and the ASU-led Algae Testbed Public-Private Partnership have made a one-year agreement with Health Enhancement Products, Inc., which investigates and licenses algae-derived, high-value bioactive molecules that benefit human and animal health.
The bacterial outer envelope is densely packed with proteins that form small pores and facilitate the passage of nutrients, toxins and signaling molecules. Professors Timm Maier and Sebastian Hiller from the Biozentrum of the University of Basel now demonstrate how these transporter proteins are integrated into the outer membrane.
Biologists at the University of California, San Diego have developed a revolutionary new method for identifying and characterizing antibiotics, an advance that could lead to the discovery of new antibiotics to treat antibiotic resistant bacteria.
University of California, San Diego bioengineering professor Gert Cauwenberghs has been selected by the National Science Foundation to take part in a five-year, multi-institutional, $10 million research project to develop a computer vision system that will approach or exceed the capabilities and efficiencies of human vision.
Bug spray, citronella candles, mosquito netting - most people will do anything they can to stay away from insects during the warmer months. But those creepy crawlers we try so hard to avoid may offer substantial solutions to some of life's problems.
Researchers at Case Western Reserve University have developed an easy and versatile way of forming physical and biochemical gradients in three dimensions -- a step toward identifying the recipes that induce stem cells to generate specific tissues, including multiple tissues, such as a bone-cartilage interface. Ultimately, one of their goals is to engineer systems to manipulate stem cells to repair or replace damaged tissues and organs.
A gentler new chemistry promises cleaner and subsequently far safer pharmaceuticals. Knud J. Jensen, who developed the ground-breaking method at the University of Copenhagen, is convinced that the method will become pivotal in the development of new pharmaceuticals.
Scientists at the University of Groningen have developed an antibiotic whose activity can be controlled using light. It is possible to 'switch on' the substance immediately before use, after which it will slowly lose its activity.
A team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells. The researchers also showed where maraviroc, an HIV drug, attaches to cells and blocks HIV's entry.