Researchers at the University of North Carolina at Chapel Hill School of Medicine have 'rationally rewired' some of the cell's smallest components to create proteins that can be switched on or off by command. These 'protein switches' can be used to interrogate the inner workings of each cell, helping scientists uncover the molecular mechanisms of human health and disease.
Scientists have revealed a new technique to introduce disease-blocking bacteria into mosquitoes, with promising results that may halt the spread of diseases such as dengue, yellow fever and potentially malaria.
The accomplishment provides a much-needed resource for scientists eager to uncover the true mechanisms of human stem cell biology. It also enables them to explore new tactics to treat inflammatory bowel disease or to ameliorate the side effects of chemotherapy and radiation, which often damage the gut.
One of the major obstacles to growing new organs _ replacement hearts, lungs and kidneys _ is the difficulty researchers face in building blood vessels that keep the tissues alive, but new findings from the University of Michigan could help overcome this roadblock.
Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers.
Crucial assumptions underlying multi-toxin crops don't always apply, a University of Arizona study shows. The results help explain why one major pest is evolving resistance faster than predicted and offer ideas for more sustainable pest control.
Explosive growth in the field of tissue engineering and regenerative medicine has led to innovative and promising applications and techniques, many of which are now being tested in human clinical trials.
A chromosome is rarely found in the shape we are used to seeing in biology books, that is to say the typical double rod shape. It is usually 'diluted' in the nucleus and creates a bundle that under the microscope appears as a messy tangle. A research coordinated by the scientists at SISSA of Trieste has now developed and studied a numeric model of the chromosome that supports the experimental data and provides a hypothesis on the bundle's function.
A team of Stanford University bioengineers has taken computing beyond mechanics and electronics into the living realm of biology. They detail a biological transistor made from genetic material - DNA and RNA - in place of gears or electrons. The team calls its biological transistor the 'transcriptor'.
Like tiny, crawling compass needles, whole living cells and cell fragments orient and move in response to electric fields - but in opposite directions, scientists at the University of California, Davis, have found. Their results could ultimately lead to new ways to heal wounds and deliver stem cell therapies.