Researchers have developed a scalable, next-generation platelet bioreactor to generate fully functional human platelets in vitro. The work is a major biomedical advancement that will help address blood transfusion needs worldwide.
Scientists have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents. The technique can be used to map all of the 'epigenetic marks' on the DNA within a single cell.
Recent advances in imaging technology are transforming how scientists see the cellular universe, showing the form and movement of once grainy and blurred structures in stunning detail. But extracting the torrent of information contained in those images often surpasses the limits of existing computational resources. Now, researchers have created a new computational method to rapidly track the three-dimensional movements of cells in such data-rich images.
Scientists were able to measure the amount of protein molecules in living human cells required to form an important structure of the chromosome, the centromere. This study presents new methodologies that may also be used to unveil other biological problems.
Researchers developed a new technique to quickly uncover novel, medically relevant products produced by bacteria. Past techniques involved screening more than 10,000 samples to find a novel product, but the method yielded a novel product after screening just a few dozen soil bacteria.
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality. Stem cell researchers now report the discovery of two genetic programs responsible for taking blank-slate stem cells and turning them into both red and the array of white cells that make up human blood.