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A new bioinformatics tool to visualize transcriptomes

ZENBU, a new, freely available bioinformatics tool developed at the RIKEN Center for Life Science Technology in Japan, enables researchers to quickly and easily integrate, visualize and compare large amounts of genomic information resulting from large-scale, next-generation sequencing experiments.

Posted: Mar 11th, 2014

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Computational tool offers new insight into key biological processes

Researchers have developed a computational tool designed to guide future research on biochemical pathways by identifying which components in a biological system are related to specific biochemical processes, including those processes responsible for gene expression, cell signaling, stress response, and metabolism.

Posted: Mar 6th, 2014

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Enzyme controls transport of genomic building blocks

Our DNA and its architecture are duplicated every time our cells divide. Histone proteins are key building blocks of this architecture and contain gene regulatory information. Danish researchers show how an enzyme controls reliable and high-speed delivery of histones to DNA copying hubs in our cells. This shuttling mechanism is crucial to maintain normal function of our genes and prevent diseases as cancer.

Posted: Mar 6th, 2014

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New molecules doom proteins with kiss of death

Like mobsters following strict orders, newly engineered molecules called 'ubiquibodies' can mark specific proteins inside a cell for destruction. It's a molecular kiss of death developed at Cornell University that is paving the way for new drug therapies and powerful research tools.

Posted: Mar 5th, 2014

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World's largest antibody search engine

An internet service which allows scientists to find antibodies for use in their research is now the largest antibody search engine in a $2billion industry, and ranked number one by Google.

Posted: Feb 28th, 2014

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A bird's eye view of cellular RNAs (w/video)

Researchers have developed a new method that allows scientists to pinpoint thousands of mRNAs and other types of RNAs at once in intact cells - all while determining the sequence of letters, or bases, that identify them and reveal what they do.

Posted: Feb 27th, 2014

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Researchers X-ray living cancer cells

At Deutsches Elektronen-Synchrotron's PETRA III research light source, scientists have carried out the first studies of living biological cells using high-energy X-rays. The new method for the first time enables us to investigate the internal structures of living cells in their natural environment using hard X-rays.

Posted: Feb 27th, 2014

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Peptides imaged in unprecedented detail

Chemists from Radboud University Nijmegen and the Foundation for Fundamental Research on Matter (FOM) have succeeded in producing detailed 3D structures of selected peptides - the building blocks of proteins.

Posted: Feb 27th, 2014

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